COVERAGE / VRTX / Healthcare

VERTEX PHARMACEUTICALS INC / MA

Pharmaceutical Preparations

COVERAGE STATUSACTIVE

DATA THROUGH2025-12-31

RESEARCH REPORTS1

SELECTED FILINGS0

Fundamental matrix

Latest / 2025-12-31 · Prior / 2024-12-31 · USD · Annual periods

Revenue

$12bn

Prior / $11.02bn

Change / +8.90%

SOURCE / 2026-02-13

Operating income

$4.17bn

Prior / $-0.23bn

Change / Base not positive

SOURCE / 2026-02-13

Net income

$3.95bn

Prior / $-0.54bn

Change / Base not positive

SOURCE / 2026-02-13

Diluted EPS

$15.32

Prior / $-2.08

Change / Base not positive

SOURCE / 2026-02-13

Free cash flow

$3.19bn

Prior / $-0.79bn

Change / Base not positive

SOURCE / 2026-02-13

Gross margin

Not available

Prior / Not available

Change / Unavailable

SOURCE / Not available

Operating margin

34.77%

Prior / -2.11%

Change / +36.89 pp

SOURCE / 2026-02-13

Return on avg. equity

22.54%

Prior / -3.15%

Change / +25.69 pp

SOURCE / 2026-02-13

Debt / equity

Not available

Prior / Not available

Change / Unavailable

SOURCE / Not available

ROE uses net income divided by average opening/closing equity. FCF = operating cash flow − selected capital expenditure. Debt/equity is unavailable because a verified interest-bearing-debt series is absent; total liabilities are not substituted for debt.

Inspect source tags, dates and accession numbers

{
  "revenue": {
    "start": "2025-01-01",
    "end": "2025-12-31",
    "val": 12001300000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "frame": "CY2025",
    "tag": "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax",
    "unit": "USD"
  },
  "netIncome": {
    "start": "2025-01-01",
    "end": "2025-12-31",
    "val": 3953200000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "frame": "CY2025",
    "tag": "us-gaap:NetIncomeLoss",
    "unit": "USD"
  },
  "operatingIncome": {
    "start": "2025-01-01",
    "end": "2025-12-31",
    "val": 4173300000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "frame": "CY2025",
    "tag": "us-gaap:OperatingIncomeLoss",
    "unit": "USD"
  },
  "eps": {
    "start": "2025-01-01",
    "end": "2025-12-31",
    "val": 15.32,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "frame": "CY2025",
    "tag": "us-gaap:EarningsPerShareDiluted",
    "unit": "USD/shares"
  },
  "operatingCashFlow": {
    "start": "2025-01-01",
    "end": "2025-12-31",
    "val": 3631400000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "frame": "CY2025",
    "tag": "us-gaap:NetCashProvidedByUsedInOperatingActivities",
    "unit": "USD"
  },
  "capex": {
    "start": "2025-01-01",
    "end": "2025-12-31",
    "val": 437600000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "frame": "CY2025",
    "tag": "us-gaap:PaymentsToAcquirePropertyPlantAndEquipment",
    "unit": "USD"
  },
  "totalAssets": {
    "end": "2025-12-31",
    "val": 25643000000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "tag": "us-gaap:Assets",
    "unit": "USD"
  },
  "totalLiabilities": {
    "end": "2025-12-31",
    "val": 6977200000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "tag": "us-gaap:Liabilities",
    "unit": "USD"
  },
  "shareholdersEquity": {
    "end": "2025-12-31",
    "val": 18665800000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "tag": "us-gaap:StockholdersEquity",
    "unit": "USD"
  },
  "currentAssets": {
    "end": "2025-12-31",
    "val": 11201000000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "tag": "us-gaap:AssetsCurrent",
    "unit": "USD"
  },
  "currentLiabilities": {
    "end": "2025-12-31",
    "val": 3861200000,
    "accn": "0000875320-26-000056",
    "fy": 2025,
    "fp": "FY",
    "form": "10-K",
    "filed": "2026-02-13",
    "tag": "us-gaap:LiabilitiesCurrent",
    "unit": "USD"
  }
}

Financial trend system

Annual financial trends are summarized in the accessible table below.

Annual figures / accessible table

Period end	Revenue	Net income	Free cash flow	EPS
2025-12-31	$12bn	$3.95bn	$3.19bn	$15.32
2024-12-31	$11.02bn	$-0.54bn	$-0.79bn	$-2.08
2023-12-31	$9.87bn	$3.62bn	$3.34bn	$13.89
2022-12-31	$8.93bn	$3.32bn	$3.93bn	$12.82

Valuation context

Historical snapshot / 2026-09-17. Annual accounting period / 2025-12-31. Not current, TTM or forward valuation.

Dated ratios / eligible same-method sector sample
Measure	Snapshot value	Historical median	Sector median	Peer count
P/E	33.70x	Unavailable	27.08x	10
P/S	10.90x	Unavailable	6.63x	10
P/B	7.01x	Unavailable	7.31x	8
EV / EBITDA	Unavailable	Unavailable	Unavailable	0
FCF yield	2.44%	Unavailable	3.88%	8

Annual denominators, not TTM or forward. Capitalization-based measures use estimated market capitalization from the dated quote snapshot. ADR/share-basis uncertainty is excluded. No comparable historical-multiple series or EV/EBITDA is available. Sector samples are equal-weight medians of this publication’s eligible covered companies; fiscal periods differ. No fair value or price target is implied.

Source: Yahoo Finance completed daily-bar snapshot; not live; market cap estimated using SEC shares at 2026-07-31 DAILY-BAR SOURCE ↗

Retained price snapshot and capitalization estimate

{
  "currentPrice": 516.34,
  "tradingDate": "2026-09-17",
  "marketCap": 130872013498.16,
  "source": "Yahoo Finance completed daily-bar snapshot; not live; market cap estimated using SEC shares at 2026-07-31"
}

Company & operating context

VERTEX PHARMACEUTICALS INC / MA is an SEC-reporting issuer listed on NASDAQ under VRTX. Its SEC industry description is Pharmaceutical Preparations. This profile organizes annual financial disclosures for research; sector labels are editorial groupings, not GICS classifications.

Drug developers, device manufacturers and care providers depend on distinct clinical, reimbursement and operating economics.

Segment-level revenue is not included in this standardized dataset. Consult the business and segment notes in the linked annual filing for the issuer’s actual reporting segments.

Filing timeline

No reading guide selected for this issuer. Annual sources remain linked below.

Research archive

HR-0150VRTXCompany Research

VRTX: reading the FY2025 financial structure ↗

VERTEX PHARMACEUTICALS INC / MA

Research abstract

Annual revenue of USD 12.001 billion and net income of USD 3.953 billion for the period ended 2025-12-31.

DATA THROUGH2025-12-312 MIN READPUBLISHED 2026-09-26

Sector context & risk factors

Patent expiry, trial outcomes, reimbursement changes, litigation and acquisition integration.

Product concentration, research investment, utilization, reimbursement and cash generation.

HEALTHCARE SYSTEM ↗

Sources & dates

SEC annual filing · 2025-12-31 ↗Source date 2026-02-13
SEC annual filing · 2024-12-31 ↗Source date 2026-02-13
SEC annual filing · 2023-12-31 ↗Source date 2026-02-13
SEC annual filing · 2022-12-31 ↗Source date 2025-02-13
SEC issuer record ↗Source date 2026-09-18